Personalised Medicine: Use Case Laboratory

Gaston Lab is monitoring software for the clinical chemical laboratory. It takes into account the patient's medical history (e.g. medication, lab) and automatically links this knowledge to a series of protocols and factors. It immediately reports potential hazardous situations. In this way Gaston helps lab professionals to quickly advise on individual patient care. Gaston Lab makes your job easier. It constantly checks the work in your laboratory. You can use it for semi-automated consultation, validation of new tests, context-dependent reference values and retrospective data retrieval. Gaston Lab is used in conjunction with existing EHR/EMR and Laboratory systems upgrading those to support Personalised Medicine.

Gaston Lab provides relevant reports:

•          Substantial reduction in the number of manually generated consultations

For an adequate interpretation of, for example, the concentration of methyl malonic acid and homo-cysteine, in addition to your laboratory results, patient age and kidney function, you also need information about vitamin supplementation and the medical question behind the laboratory test. Gaston Lab uses this information when compiling an automated interpretation. Manual adjustment is then only needed in a single case.

•          Analysis for context-dependent reference or cut-off values of the ARR

According to applicable guidelines, aldosterone and renin should only be analysed if all interfering medication has been stopped beforehand. In practice, however, it appears that RAAS modulating drugs were used in more than half of the cases. Moreover, there is great heterogeneity in number and type. In addition to medication use, blood pressure and electrolyte balance also play a role. Gaston Lab automatically provides the comprehensive interpretation of the aldosterone-renin ratio (ARR).

•          Screens faster than a clinician

Gaston Lab can detect heparin-induced thrombosis faster. It can be a HIT a few days earlier on the track than a clinician. This allows timely intervention if heparin is contraindicated.